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When you visit San Francisco for the first time, visiting Alcatraz is definitely a must-do. The Rock, as Alcatraz is known locally, was originally a lighthouse and a military out post and prison before becoming a federal prison. The likes of Al Capone, among others, served their time here. The tour takes you from the shore to this ominous island and the guides are all well-informed and always ready to answer your questions. The inherent drama of Alcatraz itself makes it worth seeing, but the added touches and expert treatment by the guides only underscore how essential it is to see this dramatic facility when you are in the Bay Area.

People who love books love Litquake, the yearly literary festival held every fall in San Francisco. Renowned authors are on hand for lectures and book signings, and interesting panels, workshops and parties are also part of what makes Litquake such an essential event for both readers and writers of all backgrounds. One of the highlights of this event is the three-hour Lit-Crawl through the Mission District that features stops at galleries, bookstores, bars and cafes.

For a look back that stretches all the way to the nation's colonial period, check out the awe-inspiring exhibits at the de Young Museum. This venue was first opened in 1895 and holds the distinction of being the city's oldest, most diversified museum. Even though it was remodeled in 2005 and several of its exhibits were updated, it still stands as one of the world's most fascinating collections of African, Oceanic, and pan-American art. This is highly worth checking out!