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If you're a fan of blues music, you will want to attend Buddy Guy's Legends in Chicago. This iconic blues bar is owned by the legendary blues musician Buddy Guy himself, and it's one of the best places in the country to catch a live blues performance. Over the years, some of the biggest names in music have graced the stage at Buddy Guy's Legends, including Van Morrison, Bo Diddley, The Rolling Stones, Lou Rawls, ZZ Top, John Mayer, Stevie Ray Vaughan, and many more. It's a must-visit spot for music lovers visiting Chicago.

The Museum of Science and Industry is a fascinating place to visit if you want to learn more about the Earth, the human body, technology, and science. With over 2,000 exhibits spread across 75 halls that cover about 14 acres, the museum opened in 1933 and is now the biggest science museum in the Western Hemisphere. In 2009, the museum had a record attendance of over 1.6 million guests, making it the third-largest cultural attraction in Chicago. The museum has a range of permanent exhibits, including a working coal mine, a 3,500-square-foot model railroad, a German Submarine captured in World War II, and a NASA spacecraft used for the Apollo 8 mission in 1968. Additionally, visitors can experience flight simulators, military crafts, an assembly line replica, a 40-foot water vapor tornado, a 13-foot interactive heart, and much more.