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Laugh until your sides are in stitches at the Helium Comedy Club, the most popular comedy club in Philly. Listen to the stylings of all your favorite comedians—from amateur locals to televised professionals—at this intimate nightlife venue. Choose a seat at the bar or at a table near the stage, and don’t forget to bring your funny bone!

Take a walk along the waterfront at Penn’s Landing and you may find some of the best shows and entertainment in the city, from Screening Under the Stars to the Olympic-sized RiverRink. This landmark site provides a perfect music and festival venue that hosts several concerts and performances throughout the year.

Take a photo with one of the country’s founding fathers! No trip to Philadelphia is complete without seeing the Benjamin Franklin National Memorial, located in the Franklin Institute’s rotunda. This Pennsylvanian landmark and attraction honors Benjamin Franklin, Philadelphia’s most famous citizen, with a colossal 20-foot-tall statue made of white marble.

Learn about the history of medicine at the Mütter Museum. This unique museum showcases a collection of attractions like medical oddities and artifacts, wax models, antique equipment and anatomical and pathological specimens. See the 200-year-old history of modern American medicine traced out before your very eyes, as well as current breakthroughs in the field.