Barbara Bennett, MD

No trip to San Francisco is complete without a visit to Fisherman's Wharf. This highly popular attraction is truly a requisite stop as it seamlessly combines the area's unmistakable natural beauty, commercial prowess, and maritime heritage all in one place. You'll want to save a whole afternoon to take it all in, as you will be struck by the impressive selection of one-of-a-kind shops, unforgettable lookout points and excellent restaurants. And speaking of restaurants, you can't visit Fisherman's Wharf without sampling such tasty delicacies as Dungeness crab and clam chowder.

For a look back that stretches all the way to the nation's colonial period, check out the awe-inspiring exhibits at the de Young Museum. This venue was first opened in 1895 and holds the distinction of being the city's oldest, most diversified museum. Even though it was remodeled in 2005 and several of its exhibits were updated, it still stands as one of the world's most fascinating collections of African, Oceanic, and pan-American art. This is highly worth checking out!

Cycling is considered a legitimate way to get around San Francisco, and the San Francisco Bicycle Coalition does its best to make sure that safety is everyone's first priority. Several of the best bike trails in the city are posted, along with detailed reviews, on their website.