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The San Francisco 49ers are part of the National Football League (NFL) and have the distinction of being the city's longest-tenured professional sports franchise. The team first hit the gridiron in 1946. They moved into Candlestick Park as their home stadium in 1971 and won five Superbowl titles in the 1980s and 1990s. The team has also produced its share of star players that include Joe Montana, Steve Young, and Jerry Rice.

People who love books love Litquake, the yearly literary festival held every fall in San Francisco. Renowned authors are on hand for lectures and book signings, and interesting panels, workshops and parties are also part of what makes Litquake such an essential event for both readers and writers of all backgrounds. One of the highlights of this event is the three-hour Lit-Crawl through the Mission District that features stops at galleries, bookstores, bars and cafes.

Biscuits and Blues not only brings you some of the best live blues music and entertainment this side of Memphis, but it also offers some of the tastiest food that features its own brand of southern flair. The venue has earned its reputation as one of the best blues clubs in the country, as it regularly features some of the world's most famous bluesmen on its stage. And if blues isn't the only thing you're hungry for, you'll also find such inviting menu items as hot biscuits, fried catfish, and spicy chicken to satisfy your non-musical appetite, as well.